Skip to content
All news
General

3 Under-the-Radar Biotech Takeover Targets for the Next Pharma Buying Spree

Big pharma is gearing up for a new wave of acquisitions targeting mid-cap biotech companies, driven by looming patent expirations on blockbuster drugs. Three under-the-radar biotechs have emerged as prime targets, but only one combines a depressed valuation with a commercial product already gaining market share.

June 25, 2026
2 min read
Source: 24/7 Wall St.
Share:

As patent cliffs loom for major drugmakers, Big Pharma is preparing for a new buying spree targeting mid-cap biotech companies, according to a report by 24/7 Wall St. The report warns that acquirers may have to overpay to secure deals or risk losing significant revenue.

Details

The report identified three mid-cap biotech companies as potential acquisition targets, without naming them. One stands out for combining a depressed valuation with a commercial product that is already gaining traction. These companies have quietly positioned themselves as attractive targets by developing promising pipelines or approved products.

Context

Patent cliffs are the main driver of this trend. As exclusivity expires for key drugs like AbbVie's (ABBV) Imbruvica and Bristol-Myers Squibb's (BMY) Opdivo, these companies need to replace lost revenue. Acquiring smaller biotechs is faster and often cheaper than internal R&D.

What This Means for Investors

For investors, these mid-cap biotechs may offer opportunities ahead of potential acquisition announcements, which typically boost stock prices. However, the risk is that deals may not materialize, leading to stock declines. Companies with commercial products and low valuations are the most attractive targets.

Frequently Asked Questions

Patent cliffs on blockbuster drugs are forcing Big Pharma to seek replacements by acquiring mid-cap biotech companies.

Found this useful? Share it

Share:
This article was rewritten in Wrqti's editorial style based on information from the original source above. Content is informational only — not investment advice.