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Merck Q1 2026 Earnings Beat Estimates, Raises EPS Guidance

Merck exceeded Q1 2026 expectations, with Keytruda sales surging 15%. The company raised its annual EPS guidance but tightened its revenue outlook, signaling caution for H2.

April 30, 2026
2 min read
Source: Zacks
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Key Numbers

revenue
12.5B
eps
2.45

Merck & Co., Inc. (NYSE: MRK) reported first-quarter 2026 results that surpassed analyst estimates, driven by strong growth of its blockbuster cancer drug Keytruda. Revenue came in at $12.5 billion, above the consensus of $12.2 billion, while earnings per share (EPS) of $2.45 beat the $2.30 estimate.

Key Financial Results

MetricQ1 2026ConsensusYoY Change
Revenue$12.5B$12.2B+8%
EPS$2.45$2.30+12%
Net Income$3.8B-+10%

Highlights from the Report

Merck attributed the beat to Keytruda, which saw a 15% year-over-year sales increase to $5.2 billion. Gardasil and Lynparza also contributed positively.

Forward Guidance

The company raised its full-year 2026 EPS guidance to $8.50-$8.70 (from $8.40-$8.60) but narrowed its revenue guidance to $48.5-$49.5 billion (from $48.5-$50.0 billion), indicating caution for the second half.

Stock Impact

MRK shares rose 1.2% in pre-market trading following the announcement. The stock is up approximately 10% year-to-date.

What This Means for Investors

Merck's results demonstrate the strength of its core business, but the narrowed revenue guidance may raise questions about growth sustainability. Focus remains on Keytruda's performance as patent expirations approach.

Frequently Asked Questions

Merck's Q1 2026 revenue was $12.5 billion, beating the consensus estimate of $12.2 billion.

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This article was rewritten in Wrqti's editorial style based on information from the original source above. Content is informational only — not investment advice.