What is the expense ratio of XLV?

XLV has an annual expense ratio of just 0.59%.

Which two companies control 90% of the obesity drug market?

Eli Lilly (LLY) and Pfizer (PFE) together control 90% of the obesity drug market.

Does XLV hold shares of Eli Lilly and Pfizer?

Yes, XLV holds shares of both Eli Lilly and Pfizer in its portfolio.

What was XLV's one-year return?

XLV returned 21.61% over the past year.

One Fund Holds 90% of Obesity Drug Market for 0.59% Fee

Eli Lilly and Pfizer together command 90% of the growing obesity drug market. The Health Care Select Sector SPDR Fund (XLV) provides investors exposure to both companies with an annual expense ratio of just 0.59%.

July 9, 2026

2 min read

Source: 24/7 Wall St.

Key Numbers

XLV one year return

21.61%

XLV ten year return

159.84%

XLV expense ratio

0.59%

obesity market share two companies

90%

The Health Care Select Sector SPDR Fund (NYSEARCA:XLV) is the default healthcare allocation for millions of investors, and for good reason. XLV owns the entire S&P 500 healthcare complex in one ticker: insurers, device makers, biotech, and Big Pharma. It has returned 21.61% over the past year and 159.84% over ten years.

Market Details

According to a report by 24/7 Wall St., Eli Lilly (NYSE:LLY) and Pfizer (NYSE:PFE) together control 90% of the booming obesity drug market. This gives XLV significant exposure to this promising sector, as both stocks are part of the fund's portfolio.

Fund Advantages

In addition to broad exposure, XLV boasts a very low expense ratio of just 0.59% annually, making it a cost-effective option for investors looking to invest in healthcare without picking individual stocks.

Context

The obesity drug market is experiencing explosive growth as demand for effective weight-loss treatments rises. Eli Lilly leads with its drug Zepbound, while Pfizer is developing its own treatments. Amgen (NASDAQ:AMGN) is also entering the space.

What It Means for Investors

XLV offers an easy, low-cost way for investors to benefit from the growth of the obesity drug market without having to pick winners. However, investors should consider the risks associated with sector concentration.

Frequently Asked Questions

The Health Care Select Sector SPDR Fund (XLV) is an exchange-traded fund that tracks the performance of the healthcare sector in the S&P 500.

Found this useful? Share it

This article was rewritten in Wrqti's editorial style based on information from the original source above. Content is informational only — not investment advice.